Doctoral Thesis: November 27, 2020

Marianne Ruud

MSc Marianne Ruud will be defending the thesis "Regulation of cardiomyocyte structure and function by workload" for the degree of Philosophiae Doctor (PhD).

Principal Supervisor: Professor William E. Louch, University of Oslo

Given topic: "Central fatigue in humans: underlying mechanisms and effects of stimulants, training and mental mindset".

Trial lecture: Nov. 27, 2020 10:15 AM
Public Defence: Nov. 27, 2020 12:15 PM

Digital Trial Lecture and Public Defence will be held as a video conference over Zoom.


Latest publication (July 2020)

Kaja K. Bergo; Anne C. Larstorp; Pavel Hoffmann; Ulla Hjørnholm; Alessandro Cataliotti; Aud Høieggen; Morten Rostrup and Fadl Elmula M. Fadl Elmula

Renal sympathetic denervation lowers systemic vascular resistance in true treatment-resistant hypertension

Read the article in Blood Press. http://doi: 10.1080/08037051.2020.1789446

Latest publication (June 2020)

Michael Frisk; Maren Høyland; Lili Zhanga; Marco Antonio Vindas; Øyvind Øverlid and Ida Beitnes Johansen

Intensive smolt production is associated with deviating cardiac morphology in atlantic salmon

Read in Aquaculture.


Doctoral Thesis: June 3, 2020

Arne Olav Melleby

MSc Arne Olav Melleby will be defending his thesis: “Cardiac remodeling responses to increased afterload: Roles and regulation of cell surface proteoglycans and integrins” for the degree of PhD (Philosophiae Doctor).

Principal Supervisor: Ida Gjervold Lunde, University of Oslo.

Given topic: “The COVID19 pandemic - implications for translational cardiovascular research”.

Trial lecture: June 3, 2020 9:15 AM

Public Defence: June 3, 2020 11:15 AM

Digital Trial Lecture and Public Defence will be held as a video conference over Zoom.


Latest publication (May 2020)

Markus Borge Harbo; Einar Sjaastad Nordén; Jagat Narula; Ivar Sjaastad and Emil Knut Stenersen Espe

Quantifying Left Ventricular Function in Heart Failure: What Makes a Clinically Valuable Parameter?

Read the article in Progress in Cardiovascular Diseases. Available online June 2, 2020.

Doctoral Thesis: May 4, 2020

Sabrina Bech Matheisen 5x7

MSc Sabrina Bech Mathiesen will be defending her thesis:
Exploring intracellular connections of syndecan-2 and -4 in the heart” for the degree of PhD (Philosophiae Doctor).

Given topic: “Proteoglycans in Cardiac Disease”.

Trial lecture: May 4, 2020 10:15 AM
Public Defence: May 4, 2020 12:15 PM

Digital Trial Lecture and Public Defence will be held as a video conference over Zoom.

Principal Supervisor: Researcher Cathrine Rein Carlson, University of Oslo


Latest publication (April 2020)

Hypertension May2020

Raffaele Altara; Gustavo J. J. da Silva; Michael Frisk; Francesco Spelta; Fouad Zouein; William E. Louch; George W. Booz and Alessandro Cataliotti

Cardioprotective Effects of the Novel Compound Vastiras in a Preclinical Model of End-Organ Damage

Read the article in Hypertension

Hypertension. 2020;75:1195-1204. DOI: 10.1161/ HYPERTENSIONAHA.120.14704

Latest publication (March 2020)

Circulation Research cover March 27, 2020

Kiarash Tazmini, Michael Frisk, Alexandre Lewalle, Martin Laasmaa, Stefano Morotti, David B. Lippsett, Ornella Manfra, Jonas Skogestad, Jan Magnus Aronsen, Ole M. Sejersted, Ivar Sjaastad, Andrew G. Edwards, Eleonora Grandi, Steven A. Niederer, Erik Øie and William E. Louch

Hypokalemia promotes arrhytmia by distinct mechanisms in atrial and ventricular myocytes

Read the article in Circulation Research

Circulation Research. 2020;126:889–906. DOI: 10.1161/CIRCRESAHA.119.315641

Doctoral Thesis: March 12, 2020

Naiyereh M. Zadeh

MSc Naiyereh Mohammadzadeh will be defending her thesis “Roles of the proteoglycans lumican and fibromodulin in cardiac remodeling following pressure overload” for the degree of PhD (Philosophiae Doctor).

Given topic: “Atrial fibrillation: Pathophysiological mechanisms and treatment options”.

Trial lecture: Mar. 12, 2020 10:15 AM
Public Defence: Mar. 12, 2020 1:15 PM

Venue: Auditorium røntgenavdelingen, Ullevål sykehus, Bygg 6 - Midtblokken

Principal Supervisor: Professor II Theis Tønnessen, University of Oslo


Doctoral Thesis: March 4, 2020

Åsmund Treu Røe

Cand.med. Åsmund Treu Røe will defend his thesis "Heart failure beyond global systolic dysfunction – active, passive and regional mechanisms of diastolic dysfunction" for the degree of PhD (Philosophiae Doctor).

Given topic: "Advantages, disadvantages and alternatives to left ventricular ejection fraction measurements"

Trial lecture: Mar. 4, 2020 11:00 AM

Public Defence: Mar. 4, 2020 1:00 PM

Principal Supervisor: Professor II William Edward Louch, Institute of Clinical Medicine, University of Oslo

Venue: Møterom IEMF (room 0704025) , Building 7, 4th floor,
Institutt for eksperimentell medisinsk forskning, Oslo universitetssykehus HF, Ullevål, Kirkeveien 166


Doctoral Thesis: February 13, 2020

Andreas Romaine

MSc Andreas Romaine will defend his thesis "Proteoglycans and integrins as keyregulators of cardiac remodelling in response to increased left ventricular afterload" for the degree of PhD (Philosophiae Doctor).

Given topic: Mechanisms of hypertension as pathogenic factor in cardiovascular disease.

Trial lecture: Feb. 13, 2020 10:15 AM

Public Defence: Feb. 13, 2020 1:15 PM

Venue: Auditoriet 1 et., Kreftsenteret (bygning 11), Ullevål sykehus, Kirkeveien 166

Supervisor: Professor II Geir Christensen, Faculty of Medicine, University of Oslo


Latest publication (February 2020)


Naiyereh Mohammadzadeh; Arne Olav Melleby; Sheryl Palmero; Ivar Sjaastad; Shukti Chakravarti; Kristin V. T. Engebretsen; Geir Christensen; Ida G. Lunde and Theis Tønnessen

Moderate loss of the extracellular matrix proteoglycan lumican attenuates cardiac fibrosis in mice subjected to pressure overload

Read the article in Cardiology

PM:31968347. DOI: 10.1159/000505318

Young Investigator Award

ESC Logo

Karoline Bjarnesdatter Rypdal has been awarded Runner Up in the YIA Poster Competition at the ESC Heart Failure Winter Meeting in Les Diablerets, January 2020.

Among more than 150 contesters, she presented the abstract: "The secreted glycoprotein ADAMTSL2 is up-regulated in heart failure and directs anti-fibrotic signalling in cardiac fibroblats"

Congratulations for the Young Investigator Award!

Latest publication (January 2020)

American journal of physiology. , 2020, Vol.318

Emil K S Espe, Jan M Aronsen, Einar S Nordén, Lili Zhang and Ivar Sjaastad.

Regional Right Ventricular Function in Rats: A Novel Magnetic Resonance Imaging Method for Measurement of Right Ventricular Strain

Read the article in American Journal of Physiology-Heart and Circulatory Physiology

Am J Physiol Heart Circ Physiol , 318 (1), H143-H153 2020 Jan 1
PMID: 31774693 DOI: 10.1152/ajpheart.00357.2019

Doctoral Thesis: December 6, 2019

Fadila 2019

Cand.med. Fadila Telarevic Cero will defend her thesis “Hypoxia-Induced Pulmonary Hypertension and Cardiac Dysfunction; The Role of Inflammasomes and related Cytokines” for the degree of PhD (Philosophiae Doctor).
Given topic: "Heart failure in COPD - mechanisms, diagnosis and treatment."

Trial lecture: December 6, 2019 10:15 AM

Public Defence: December 6, 2019 1:15 PM

Venue: Auditorium 1, Kreftsenteret, Bygg 11, Oslo universitetssykehus, Ullevål, Kirkeveien 166

Supervisor: Professor II Ole Henning Skjønsberg, Faculty of Medicine, University of Oslo


Super-resolution and Confocal Microscopy


Our institute is one of the nodes in a core facility for super-resolution and confocal microscopy supported by Helse Sør-Øst. This core facility includes two additional nodes located at Radiumhospitalet (Montebello) and Rikshospitalet (Gaustad).

A core facility is a laboratory with particularly advanced equipment that serves researchers both within and outside the unit.

Read more about:
Core Facility Super-resolution and Confocal Microscopy, Ullevål

K. G. Jebsen Centre for Cardiac Research at University of Oslo


K.G. Jebsen Centre for Cardiac Research is directed by Professor Ivar Sjaastad: "Our primary objective is to better understand the mechanisms of heart failure. Specifically, we will identify mechanisms regulating myocardial stiffness, and new therapeutic targets of diastolic dysfunction."

The centre comprises six research groups at University of Oslo; of which three are located at Ullevål Hospital, two at Rikshospitalet and one at Radiumhospitalet.

Group leaders: Ivar Sjaastad (Centre leader), Geir Christensen, (Deputy leader), William E. Louch, Camilla Raiborg, Thor Edvardsen and Lars Gullestad
Associated partners: Alessandro Cataliotti, Llewelyn Roderick (University of Cambridge), Joakim Sundnes (Simula) and Kjetil Taskén
Administrative coordinator: Emil Espe

Read more about the K.G. Jebsen Centre for Cardiac Research

Metode-banner 2015 utsnitt

Institute for Experimental Medical Research (IEMR)

Institutt for eksperimentell medisinsk forskning (IEMF)

Click for Address Information...
Click for Archive…


Webmaster Vidar, IEMF